Best Bets for NCAA Basketball Picks Against the Spread for Saturday, February 22
Published 6:23 pm Friday, February 21, 2025
The Cal Baptist Lancers versus the Grand Canyon Antelopes is one of many compelling options on Saturday in college basketball action — suggested picks against the spread for 10 games are available here.
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Today’s NCAA Men’s Basketball Picks ATS
ATS Pick: Cal Baptist +9.5 vs. Grand Canyon
- Matchup: Cal Baptist Lancers at Grand Canyon Antelopes
- Time: 8 p.m. ET
- Date: February 22
- Computer Projection: Grand Canyon by 5.6 points (Bet now on BetMGM)
- Spread: Grand Canyon (-9.5)
- TV Channel: ESPN+
- Live Stream: Watch this game on ESPN+
ATS Pick: Ole Miss +1.5 vs. Vanderbilt
- Matchup: Ole Miss Rebels at Vanderbilt Commodores
- Time: 3:30 p.m. ET
- Date: February 22
- Computer Projection: Ole Miss by 2.2 points (Bet now on BetMGM)
- Spread: Vanderbilt (-1.5)
- TV Channel: SEC Network
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
ATS Pick: TCU +7.5 vs. Cincinnati
- Matchup: TCU Horned Frogs at Cincinnati Bearcats
- Time: 12 p.m. ET
- Date: February 22
- Computer Projection: Cincinnati by 3.9 points (Bet now on BetMGM)
- Spread: Cincinnati (-7.5)
- TV Channel: ESPN2
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
ATS Pick: Kentucky +9.5 vs. Alabama
- Matchup: Kentucky Wildcats at Alabama Crimson Tide
- Time: 6 p.m. ET
- Date: February 22
- Computer Projection: Alabama by 5.9 points (Bet now on BetMGM)
- Spread: Alabama (-9.5)
- TV Channel: ESPN
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
ATS Pick: West Virginia +11.5 vs. Texas Tech
- Matchup: West Virginia Mountaineers at Texas Tech Red Raiders
- Time: 1 p.m. ET
- Date: February 22
- Computer Projection: Texas Tech by 8.1 points (Bet now on BetMGM)
- Spread: Texas Tech (-11.5)
- TV Channel: ESPN+
- Live Stream: Watch this game on ESPN+
Bet on this or any men’s college basketball matchup at BetMGM.
ATS Pick: McNeese -10.5 vs. Texas A&M-CC
- Matchup: Texas A&M-CC Islanders at McNeese Cowboys
- Time: 5 p.m. ET
- Date: February 22
- Computer Projection: McNeese by 13.9 points (Bet now on BetMGM)
- Spread: McNeese (-10.5)
- TV Channel: ESPN+
- Live Stream: Watch this game on ESPN+
ATS Pick: UNC Greensboro -2.5 vs. Mercer
- Matchup: UNC Greensboro Spartans at Mercer Bears
- Time: 2 p.m. ET
- Date: February 22
- Computer Projection: UNC Greensboro by 5.2 points (Bet now on BetMGM)
- Spread: UNC Greensboro (-2.5)
- TV Channel: ESPN+
- Live Stream: Watch this game on ESPN+
ATS Pick: Georgia +18.5 vs. Auburn
- Matchup: Georgia Bulldogs at Auburn Tigers
- Time: 4 p.m. ET
- Date: February 22
- Computer Projection: Auburn by 15.9 points (Bet now on BetMGM)
- Spread: Auburn (-18.5)
- TV Channel: ESPN
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
ATS Pick: BYU +7.5 vs. Arizona
- Matchup: BYU Cougars at Arizona Wildcats
- Time: 10 p.m. ET
- Date: February 22
- Computer Projection: Arizona by 4.9 points (Bet now on BetMGM)
- Spread: Arizona (-7.5)
- TV Channel: ESPN
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
ATS Pick: SMU +1.5 vs. Clemson
- Matchup: Clemson Tigers at SMU Mustangs
- Time: 4 p.m. ET
- Date: February 22
- Computer Projection: SMU by 1 points (Bet now on BetMGM)
- Spread: Clemson (-1.5)
- TV Channel: ACC Network
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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